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Cancer Stem Cell Markers and Related Network Pathways - Original PDF
Cancer Stem Cell Markers and Related Network Pathways - Original PDF
نویسندگان: Shihori Tanabe خلاصه: This book entitled “Cancer Stem Cell Markers and Related Network Path-ways” is about cancer stem cell (CSC) markers and the molecular network pathways. CSCs play an important role in the cancer drug resistance, metastasis and recurrence. Epithelial-mesenchymal transition (EMT) is closely related to CSC phenotype. This book covers various aspects of the molecular networks related to CSCs including the important phenotypic change such as EMT. Readers will discover the importance of the identification of CSC markers and EMT-related molecules in CSC network pathways. The CSC signaling pathways and EMT molecular network pathways attract researchers in the field to define the cancer therapeutic targets. Cancer environment is important in the acquisition of CSC phenotype in cells. The revealing of this CSC mystery is across 7 chapters. The topic of this book is particularly relevant to research in the field of cancer and stem cells, as well as the network pathways. We hope that this book helps the readers to be interested in understanding why the CSC concept is important and attractive.
Shoe Dog: A Memoir by the Creator of NIKE - PDF
Shoe Dog: A Memoir by the Creator of NIKE - PDF
نویسندگان: N.A خلاصه: In 1962, fresh out of business school, Phil Knight borrowed $50 from his father and created a company with a simple mission: import high-quality, low-cost athletic shoes from Japan. Selling the shoes from the boot of his Plymouth, Knight grossed $8000 in his first year. Today, Nike's annual sales top $30 billion. In an age of start-ups, Nike is the ne plus ultra of all start-ups, and the swoosh has become a revolutionary, globe-spanning icon, one of the most ubiquitous and recognisable symbols in the world today.
The Power of Habit: Why We Do What We Do in Life and Business - PDF
The Power of Habit: Why We Do What We Do in Life and Business - PDF
نویسندگان: Mike Chamberlain خلاصه: In The Power of Habit, award-winning business reporterCharles Duhigg takes us to the thrilling edge of scientific discoveries that explain why habits exist and how they can be changed. Distilling vast amounts of information into engrossing narratives that take us from the boardrooms of Procter & Gamble to the sidelines of the NFL to the front lines of the civil rights movement, Duhigg presents a whole new understanding of human nature and its potential. At its core, The Power of Habit contains an exhilarating argument: The key to exercising regularly, losing weight, being more productive, and achieving success is understanding how habits work. As Duhigg shows, by harnessing this new science, we can transform our businesses, our communities, and our lives.
High Performance Elastomer Materials: An Engineering Approach - Original PDF
High Performance Elastomer Materials: An Engineering Approach - Original PDF
نویسندگان: Ryszard Kozłowski; G E Zaikov; Dariusz M Bielinski خلاصه: This book presents selected papers on various aspects of rubber engineering, technology, and exploitation. The contributions range from new methods of the modification of filler surface and crosslinks structure of rubber vulcanizates, through modern functional elastomer composites, to aspects of their thermal stability, flammability, and ozone degradation.
FAMILY THERAPY Concepts, Process and Practice - Original PDF
FAMILY THERAPY Concepts, Process and Practice - Original PDF
نویسندگان: Norman Sartorius, Julian Leff, Juan José López-Ibor, Mario Maj, Ahmed Okasha خلاصه: According to the World Health Organization’s World Health Report 2001, one family in four worldwide has at least one member currently suffering from a mental disorder. This disorder often remains undiagnosed and untreated, but the behaviour of the ill person usually has a significant impact on the quality of life of the family and on the mental health of the other members of the family, and generates feelings of shame, guilt, helplessness and despair. This book provides a comprehensive picture of currently available evidence about the specific characteristics of the burden on the families of people with the various mental disorders, the coping strategies which increase or decrease this burden, the family interventions of proven efficacy, and what should be said and what should not be said to the relatives of people with the various conditions.
Knowledge-based intelligent techniques in character recognition - Original PDF
Knowledge-based intelligent techniques in character recognition - Original PDF
نویسندگان: Lakhmi C. Jain, Beatrice Lazzerini خلاصه: Knowledge-Based Intelligent Techniques in Character Recognition presents research results on intelligent character recognition techniques, reflecting the tremendous worldwide interest in the applications of knowledge-based techniques in this challenging field.This resource will interest anyone involved in computer science, computer engineering, applied mathematics, or related fields. It will also be of use to researchers, application engineers and students who wish to develop successful character recognition systems such as those used in reading addresses in a postal routing system or processing bank checks.Features
Artificial Intelligence in Medicine: Joint European Conference on Artificial Intelligence in Medicine and Medical Decision Making, AIMDM'99 Aalborg, Denmark, June 20–24, 1999 Proceedings - Original PDF
Artificial Intelligence in Medicine: Joint European Conference on Artificial Intelligence in Medicine and Medical Decision Making, AIMDM'99 Aalborg, Denmark, June 20–24, 1999 Proceedings - Original PDF
نویسندگان: Gianpaolo Molino (auth.), Werner Horn, Yuval Shahar, Greger Lindberg, Steen Andreassen, Jeremy Wyatt (eds.) خلاصه: Updates pregnancy-specific measurement instruments for examining maternal psychosocial status Discusses substantial research on maternal prenatal stress and high-risk pregnancy This book constitutes the refereed proceedings of the Joint European Conference on Artificial Intelligence in Medicine and Medical Decision Making, AIMDM'99, held in Aalborg, Denmark, in June 1999. The 27 full papers and 19 short papers presented in the book together with four invited papers were selected from 90 submissions. The papers are organized in topical sections on guidelines and protocols; decision support systems, knowledge-based systems, and cooperative systems; model-based systems; neural nets and causal probabilistic networks; knowledge representation; temporal reasoning; machine learning; natural language processing; and image processing and computer aided design.
Cultural Resources for Tourism: Patterns, Processes and Policies - Original PDF
Cultural Resources for Tourism: Patterns, Processes and Policies - Original PDF
نویسندگان: Myriam Jansen-verbeke, Gerda K. Priestley, Antonio P. Russo خلاصه: The cultural heritage of regions and communities is presently being rediscovered and valorised as a driving force in building cultural identity and as a ubiquitous resource for dynamizing cultural activities. This process can lead to the development of cultural capital with clear territorial links and, as such, a favourable incubation condition for creating sustainable and competitive forms of cultural tourism. Research on cultural resources for tourism implies both a multidisciplinary approach and methodological innovations to deal with such a complex phenomenon. The challenge to identify and map cultural heritage elements - tangible and intangible - in a pan European context has recently been dealt with in the ESPON project 1.3.3 (2004-2006). Lack of adequate definitions, poor databases, and a showcase of national and sector differences in approaching culture as 'resource' for development was the final balance of that explorative project. These findings have prompted further case study research into the study of cultural heritage, which is encapsulated in this book. This publication differs from others on cultural tourism through its emphasis on spatial dynamics, by analyzing location and behavior patterns in different tourism destinations, by identifying the parameters of change induced by tourism and, not in the least, trial and error examples in policy making. The book includes a rich variety of case studies mainly from all over Europe (but also including cases set in Israel, Cairo and India), representing the views and findings of 21 international researchers and scholars in cultural tourism, scanning unique situations in order to detect the common dynamics and impacts of tourismification. The final objective is to propose consistent directions for policy, based on empirical insights. The book contributes significantly to the understanding of cultural diversity and territorial identity, on the one hand, and to the dynamics of tourism, on the other, all of which are key issues in local and regional planning and management. As such, they should be a source of inspiration for policy-makers and an eye-opener for students, researchers and consultants in the field of cultural heritage and tourism and, hopefully, an interesting virtual trip - from Savonlinna to Cairo, from Santiago de Compostela to Sibiu - crossing and discovering a kaleidoscope of colourful and unique cultural landscapes and tourismscapes.
Travel and Tourism Public Relations: An Introductory Guide for Hospitality Managers - Original PDF
Travel and Tourism Public Relations: An Introductory Guide for Hospitality Managers - Original PDF
نویسندگان: Dennis E. Deuschl خلاصه: The opening chapter explains the recent growth of industry PR, and travel & tourism news coverage which today focuses on the considerable economic benefits of the industry. Additionally, it reviews the leading news media that covers the industry, the primary PR tools and audiences, and details the factors leading to PR's new prominence across the industry. It also provides informative sidebars with lists of key industry print media, top travel agencies, plus a Travel Industry Association of America case study of a post-9/11/2001 campaign to restore American confidence in travelling. It also includes a composite definition of PR, and tells how PR is a discipline distinctively different from publicity, propaganda, advertising, and marketing. The author notes how, over the past decade due to economic conditions, PR in many cases has been integrated with marketing communications and played an important role in both strategic and tactical marketing activities. Following this overview, the ensuing five chapters examine communications model specifics that are of special importance to the industry's major sectors: hotels/lodging establishments; restaurants; tourist attractions/destinations; and transportation services. Each of these sectors have their ownspecial messages, PR tools, and audiences. For example, meeting planners and travel agents are of most importance to hotels, while travel agents are of little importance to airlines and restaurants. Also included is a chapter about what travel employers should understand about PR The chapters will be followed by appendices that will include:The top 30 U.S. Travel & Tourism Professional/Trade Associations; and the Leading U.S. Travel & Tourism Universities. * Provides a comprehensive how-to guide for travel & tourism PR practitioners to increase profits and enhance the visibility and image of their company or client* Introduces the key domestic/international media and audiences that PR pros in travel & tourism need to target, plus what the best PR tools are to use -- including crisis communication -- along with case studies * Addresses the unique communication challenges in each major industry sector as faced by travel & tourism PR professionals through perspectives from industry experts * Features a dozen sidebar contributions by some of the industry's top PR experts and media stars* Advises industry employers about the value of PR, what it is and is not, and suggests ways to identify PR talent
Water-Based Tourism, Sport, Leisure, and Recreation Experiences - Original PDF
Water-Based Tourism, Sport, Leisure, and Recreation Experiences - Original PDF
نویسندگان: Gayle Jennings خلاصه: Written by a team of international contributors, from Australia, Europe and the USA, the text uses international case studies and examples to illustrate and highlight discussion.Contributors include: Paul Beedie, De Montfort University, UK; Kay Dimmock, Southern Cross University, Australia; Gary Easthope, University of Tasmania, Australia; Simon Hudson, University of Calgary, Canada; Gayle Jennings, Griffith University, Australia; Lilian Jonas, Jonas Consulting, USA; Les Killion, Central Queensland University, Australia; Gianna Moscardo, James Cook University, Australia; Harold Richins, Sierra Nevada College, USA; Chris Ryan, The University of Waikato, New Zealand. * A unique insight into these growing areas of the tourism industry looking at their interaction, market profiles, advantages and their effects on the environment.* International contributor team provides a wealth of perspectives and case studies* Considers future directions and impacts (positive and negative)

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