موضوعات
آموزش و پرورش
ادبیات و زبان
پزشکی، دندانپزشکی و داروسازی
تاریخ و جغرافیا
داستان و رمان
دیگر
دین و فلسفه
روانشناسی
ریاضیات و آمار
سلامتی، تناسب اندام و رژیم غذایی
شیمی و پلیمر
علوم اجتماعی و حقوق
علوم زیستی و بیوتکنولوژی
فیزیک و نجوم
کامپیوتر و اینترنت
کتابهای کودکان و داستان
کسب و کار و اقتصاد
کشاورزی و دامپزشکی و غذا
معماری
مهندسی و فناوری
هنر و تئاتر
محصولات
The coming generational storm: what you need to know about America's economic future - Original PDF
نویسندگان: خلاصه: In 2030, as 77 million baby boomers hobble into old age, walkers will outnumber strollers; there will be twice as many retirees as there are today but only 18 percent more workers. How will America handle this demographic overload? How will Social Security and Medicare function with fewer working taxpayers to support these programs? According to Laurence Kotlikoff and Scott Burns, if our government continues on the course it has set, we'll see skyrocketing tax rates, drastically lower retirement and health benefits, high inflation, a rapidly depreciating dollar, unemployment, and political instability. The government has lost its compass, say Kotlikoff and Burns, and the current administration is heading straight into the coming generational storm.But don't panic. To solve a problem you must first understand it. Kotlikoff and Burns take us on a guided tour of our generational imbalance, first introducing us to the baby boomers - their long retirement years and "the protracted delay in their departure to the next world. Then there's the "fiscal child abuse" that will double the taxes paid y the next generation. There's also the "deficit delusion" of the under-reported national debt. And none of this, they say, will be solved by any of the popularly touted remedies: cutting taxes, technological progress, immigration, foreign investment, or the elimination of wasteful government spending. So how can the United States avoid this demographic/fiscal collision? Kotlikoff and Burns propose bold new policies, including meaningful reforms of Social Security and Medicare. Their proposals are simple, straightforward, and geared to attract support from both political parties. But just in case our elected officials won't take the political risk to chart a new direction, Kotlikoff and Burns also offer a "life jacket" - guidelines for individuals to protect their financial health and retirement.
The Restorative Nature of Ongoing Connections with the Deceased: Exploring Presence Within Absence - Orginal Pdf
نویسندگان: خلاصه: The Restorative Nature of Ongoing Connections with the Deceased: Exploring Presence Within Absence (Series in Death, Dying, and Bereavement) 1st Edition by Laurie A. Burke (Editor), Edward (Ted) Rynearson
Farewell: Vital End-of-Life Questions with Candid Answers from a Leading Palliative and Hospice Physician - Epub + Converted Pdf
نویسندگان: خلاصه: Farewell: Vital End-of-Life Questions with Candid Answers from a Leading Palliative and Hospice Physician by Edward T. Creagan MD (Author), Sandra Wendel
Drop Shot - Epub + Converted PDF
نویسندگان: خلاصه: Valerie Simpson is a young female tennis star with a troubled past who's now on the verge of a comeback and wants Myron as her agent. Myron, who's also got the hottest young male tennis star, Duane Richwood, primed to take his first grand slam tournament, couldn't be happier. That is, until Valerie is murdered in broad daylight at the U.S. Open and Myron's number one client becomes the number one suspect.
Fade Away - Epub + Converted PDF
نویسندگان: خلاصه: Valerie Simpson is a young female tennis star with a troubled past who's now on the verge of a comeback and wants Myron as her agent. Myron, who's also got the hottest young male tennis star, Duane Richwood, primed to take his first grand slam tournament, couldn't be happier. That is, until Valerie is murdered in broad daylight at the U.S. Open and Myron's number one client becomes the number one suspect.Clearing Duane's name should be easy enough. Duane was playing in a match at the time of Valerie's death. But why is his phone number in Valerie's black book when he claims only to have known her in passing? Why was she calling him from a phone booth on the street? The police stop caring once they pin the murder on a man known for having stalked Valerie and seen talking to her moments before the murder. But Myron isn't satisfied. It seems too clean for him.Myron pries a bit and finds himself prying open the past where six years before, Valerie's fiancee, the son of a senator, was brutally murdered by a juvenile delinquent and a straight-A student was subsequently gunned down on the street in retaliation, his death squandered in bureaucratic files. And everyone from the Senator to the mob want Myron to stop digging.The truth beneath the truth is not only dangerous, it's deadly. And Myron may be the next victim.In novels that crackle with wit and suspense, Edgar Award winner Harlan Coben has created one of the most fascinating and complex heroes in suspense fiction—Myron Bolitar—a hotheaded, tenderhearted sports agent who grows more and more engaging and unpredictable with each page-turning appearance.
Veterinary Immunology 10E - Original PDF
نویسندگان: خلاصه: This textbook was first published in 1977, at a time when veterinary immunology was relatively new and poorly understood. Nevertheless, it was recognized, even then, that immunology held the key to many of the significant issues in veterinary medicine. The importance of immunology has not declined since then, except among those tasked with establishing college curricula. The decline in basic science instruction at colleges of veterinary medicine in favor of more clinical training has resulted in graduating a generation of veterinarians whose knowledge of immunology is minimal. Yet immunology continues to be a key science. It is central to our understanding of major veterinary issues such as vaccination, cancer, infectious diseases, and allergies. It has been tempting to dilute the contents of this text and its associated website to conform to current curricular trends. I have resisted this. Because the amount of knowledge of immunology required to obtain a veterinary degree has been progressively reduced, the need to document the science in depth has correspondingly increased. This book therefore continues to grow as the result of opening up new, exciting areas of the science. Veterinarians need to know much of this if they are to practice cutting-edge science in the 21st century. Read it, study it, and enjoy its wonderful complexity. Over the many years that this textbook has been published we have seen many changes in the science of immunology. In most cases, these changes have been gradual in nature as investigators add detail to existing knowledge. Occasionally, however, major leaps are made that effectively revolutionize the discipline—socalled paradigm shifts. For example, in the late 1990s, the concept of innate immunity was accepted. Inflammation and other processes were finally recognized as being essential components of the immune system and the dual innate and adaptive immune systems were shown to complement each other. It is interesting to note that this was not a new discovery but a new way of looking at well recognized processes. This new edition also reflects revolutionary changes in the way we think of immunology. Like the concept of innate immunity, these changes are not a result of a previously unknown process but a belated recognition of something known about since the dawn of microbiology, the body's normal microbiota. New methodologies and intensive studies have revealed that many body processes, especially immunity, are regulated by the diverse microbiota that colonizes all body surfaces. Much of immunology has had to be reassessed in the light of this new knowledge. Both innate and adaptive immunity are regulated by those organisms, especially bacteria, that live in the intestine and respiratory tract and on the skin. Many previously unexplained phenomena have now been shown to depend on the normal microbiota. As a result of this new information, the reader will encounter the microbiota at every turn in this book, plus a completely new chapter on the subject. The second new chapter deals with allergic diseases. For many years, these were readily explained by the production of IgE against allergens. The most recent information, however, has demonstrated that allergies are much more complex than this. For example, atopic dermatitis, one of the most common conditions seen by small animal veterinarians, is likely a syndrome with multiple complex causative factors. As a result, allergic and inflammatory diseases deserve a new chapter. These additions cannot, however, hide the fact that the rest of immunology also continues to move forward. Thus the mechanisms by which the body rejects gastrointestinal helminths has been clarified with the discovery of the importance of tuft cells and interleukin-33. Associated with this has been the recognition of the complex nature of innate lymphoid cells and their subpopulations. Some of these advances can be considered routine, such as the identification of new cell surface molecules and many new cytokines. New disease syndromes such as swine SCID, bovine neonatal pancytopenia, and immune-mediated keratoconjunctivitis are now described, and the pathogenesis of others such as atopic dermatitis, type I diabetes mellitus, equine laminitis, and systemic lupus are shown to be more complex than previously believed. New advances in therapy are covered, including the introduction of immune checkpoint therapy in cancer and the use of monoclonal antibody therapy and intravenous immunoglobulin therapy for immune-mediated diseases. The exciting new developments in the use of nanoparticles in vaccines and as adjuvants are now described. The significant roles of vitamins A and D as well as the aryl hydrocarbon receptor in immunity are also recognized. Advances in basic science that are now discussed include new findings on the structure and genetics of bovine antibodies, epigenetics, RNA interference, microRNA, macrophage polarization, and type 1 and type 2 immune responses. I make no apologies for the size and complexity of this text. Immunology is a complex subject that has a direct bearing on many of the most important areas of veterinary medicine. Students, as well as graduate veterinarians, ignore it at their peril. Finally, readers are strongly encouraged to visit the Evolve website for this text. The site is also constantly evolving and improving. In it you will be able to find a collection of more than 450 multiple-choice questions (with the answers!) keyed to each chapter; a set of flashcards also linked to chapters; all the text figures available as PowerPoint slides; and a collection of animations kindly provided by Dr. Abul Abbas, as well as brand new animations created for this textbook, designed to clarify some complex processes and pathways where still figures are inadequate. All the chapter references are keyed to PubMed. There are also new hand-outs that students can print off and use as a reference, should you wish. It is my hope that these assets will help you remain current in this rapidly expanding and exciting field.
Textbook of Veterinary Internal Medicine DISEASES OF THE DOG AND THE CAT EIGHTH EDITION - Original PDF
نویسندگان: خلاصه: Ensure you have ongoing access to the most reliable veterinary information available! The Textbook of Veterinary Internal Medicine, 8th Edition remains the internationally acclaimed "gold standard" in veterinary medicine with its unparalleled coverage of pathophysiology, diagnosis, and treatment of diseases affecting dogs and cats. This one-of-a-kind resource includes the latest information on topical issues such as clinical genomics, coexisting cardiac and renal diseases, minimally-invasive interventional . . .
Principles of Tissue Engineering Fifth Edition - Original PDF
نویسندگان: خلاصه: Now in its fifth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fifth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future. This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and the application of tissue-engineering techniques for food production – is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the emerging technologies in the field.![The Bill of Lading: Holder Rights and Liabilities[2019] - Original PDF](https://dl.libsan.ir/images/1/12/5_6480330a41914.jpg)
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