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Medical Ethics A Very Short Introduction Tony Hope - Original PDF
Medical Ethics A Very Short Introduction Tony Hope - Original PDF
نویسندگان: Tony Hope خلاصه: The fox represents those who pursue many ends, often unrelated and even contradictory, connected, if at all, only in some de facto way, . . . [who] lead lives, perform acts, and entertain ideas that are cen- trifugal rather than centripetal . . . seizing upon the essence of a vast variety of experiences . . . without . . . seeking to fit them into . . . any one unchanging, all-embracing, . . . unitary inner vision. Berlin gives as examples of hedgehogs: Dante, Plato, Dostoevsky, Hegel, Proust, amongst others. He gives as examples of foxes: Shakespeare, Herodotus, Aristotle, Montaigne, and Joyce. Berlin goes on to argue that Tolstoy was a fox by nature but believed in being a hedgehog. 4 Medical Ethics 2. Are you a hedgehog or a fox? I am a fox, or at least would like to be. I admire the intellectual rigour of those who try to produce a unitary vision, but I prefer the rich, contradictory, and sometimes chaotic visions of Berlin’s foxes. I do not, in this book, attempt to approach the various problems I discuss from one single moral theory. Each chapter considers an issue on which I argue for a particular position, using whatever methods of argument seem to me to be the most relevant. I have covered different areas in different chapters: genetics, modern reproductive technologies, resource allocation, mental health, medical research, and so on; and have looked at one issue in each of these areas. At the end of the book I guide the reader to other issues and further reading. The one perspective that is common to all the chapters is the central importance of reasoning and reasonableness. I believe that medical ethics is essentially a rational subject: that is, it is all about giving reasons for the view that you take, and being prepared to change your views on the basis of reasons. That is why one chapter, in the middle of the book, is a reflection on various tools of rational argument. But although I believe in the central importance of reasons and evidence, even here the fox in me sounds a note of caution. Clear thinking, and high standards of rationality, are not enough. We need to develop our hearts as well as our minds. Consistency and moral enthusiasm can lead to bad acts and wrong decisions if pursued without the right sensitivities. The novelist, Zadie Smith, has written: There is no bigger crime, in the English comic novel, than thinking you are right. The lesson of the comic novel is that our moral enthusiasms make us inflexible, one-dimensional, flat. This is a lesson we need to take into any area of practical ethics, including medical ethics. What better place to start this tour of medical ethics than at the end, with the thorny issue of euthanasia? 6 Medical Ethics Chapter 2 Euthanasia: good medical practice, or murder? Good deeds do not require long statements; but when evil is done the whole art of oratory is employed as a screen for it. (Thucydides) The practice of euthanasia contradicts one of the oldest and most venerated of moral injunctions: ‘Thou shalt not kill’. The practice of euthanasia, under some circumstances, is morally required by the two most widely regarded principles that guide medical practice: respect for patient autonomy and promoting patient’s best interests. In the Netherlands and Belgium active euthanasia may be carried out within the law. Outline of the requirements in order for active euthanasia to be legal in the Netherlands 1. The patient must face a future of unbearable, interminable suffering. 2. The request to die must be voluntary and well-considered. 3. The doctor and patient must be convinced there is no other solution. 4. A second medical opinion must be obtained and life must be ended in a medically appropriate way.
Adaptive Optics for Vision Science Principles Practices Design and Applications - Original PDF
Adaptive Optics for Vision Science Principles Practices Design and Applications - Original PDF
نویسندگان: Jason Porter, Hope Queener, Julianna Lin, Karen Thorn, Abdul A. S. Awwal خلاصه: The high transverse resolution of retinal imaging systems equipped with adaptive optics provides a unique opportunity to record these eye move- ments with very high accuracy. Putnam et al. showed that it is possible to record the retinal location of a fixation target on discrete trials with an error at least 5 times smaller than the diameter of the smallest foveal cones [63]. We used this capability to measure the standard deviation of fixation positions FIGURE 1.7 Images of the cone mosaics of 10 subjects with normal color vision, obtained with the combined methods of adaptive optics imaging and retinal densi- tometry. The images are false colored so that blue, green, and red are used to repre- sent the S, M, and L cones, respectively. (The true colors of these cones are yellow, purple, and bluish-purple). The mosaics illustrate the enormous variability in L/M cone ratio. The L/M cone ratios are (A) 0.37, (B) 1.11, (C) 1.14, (D) 1.24, (E) 1.77, (F) 1.88, (G) 2.32, (H) 2.36, (I) 2.46, (J) 3.67, (K) 3.90, and (L) 16.54. The proportion of S cones is relatively constant across eyes, ranging from 3.9 to 6.6% of the total population. Images were taken either 1° or 1.25° from the foveal center. For two of the 10 subjects, two different retinal locations are shown. Panels (D) and (E) show images from nasal and temporal retinas, respectively, for one subject; (J) and (K) show images from nasal and temporal retinas for another subject. Images (C), (J), and (K) are from Roorda and Williams [52]. All other images were made by Heidi Hofer. (See insert for a color representation of this figure.) (From Williams and Hofer [57]. Reprinted with permission from The MIT Press.) across discrete fixation trials, obtaining values that ranged from 2.1 to 6.3 arcmin, with an average of 3.4 arcmin, in agreement with previous studies [63, 64]. Interestingly, the mean fixation location on the retina was displaced from the location of highest foveal cone density by an average of about 10 arcmin (as shown in Fig. 1.8), indicating that cone density alone does not drive the location on the retina selected for fixation. This method may have interesting future applications in studies that require the submicron registra- tion of stimuli with respect to the retina or delivering light to retinal features as small as single cells. Whereas the method developed by our group can only record eye position on discrete trials, Scott Stevenson and Austin Roorda have shown that it is possible to extract continuous eye movement records from video-rate images obtained with an adaptive optics scanning laser ophthalmoscope (AOSLO) [66]. Eye movements cause local warping of the image within single video frames as well as translation between frames. The warping and translation information in the images can be used to recover a record of the eye move- ments that is probably as accurate as any method yet devised. This is illus- trated in Figure 1.9, which compares the eye movement record from the AOSLO with that from a Dual Purkinje Eye Tracker. The noise in the AOSLO trace is on the order of a few arc seconds compared to about a minute of arc for the Dual Purkinje Eye Tracker. Note also the greatly reduced overshoot following a saccade in the AOSLO trace. These overshoots are thought to be partly artifacts caused by lens wobble following the saccade and do not reflect the true position of the retinal image. The AOSLO is not susceptible to this artifact because it tracks the retinal position directly rather than relying on reflections from the anterior optics.
Diagnostic Radiology Physics: A Handbook For Teachers And Students - Original PDF
Diagnostic Radiology Physics: A Handbook For Teachers And Students - Original PDF
نویسندگان: International atomic energy agency خلاصه: This book is dedicated to students and teachers involved in programmes that train professionals for work in diagnostic radiology. It teaches the essential physics of diagnostic radiology and its application in modern medicine. As such, it is useful to graduate students in medical physics programmes, residents in diagnostic radiology and advanced students in radiographic technology programmes.
Davidson’s Self-assessment in Medicine - Original PDF
Davidson’s Self-assessment in Medicine - Original PDF
نویسندگان: Deborah Wake MB ChB (Hons) BSc PhD Diplo خلاصه: This book has been built around modern educational principles and utilises a contemporary assessment style, in line with current undergraduate and postgraduate teaching. It is designed to help and support students in their final undergraduate years and in the early years after qualification. The style is compatible with that used in modern postgraduate examinations across the world.
Fooled By Randomness - PDF
Fooled By Randomness - PDF
نویسندگان: Nassim Nicholas Taleb خلاصه: This is my book summary of Fooled by Randomness by Nassim Nicholas Taleb. My notes are informal and often contain quotes from the book as well as my own thoughts. This summary also includes key lessons and important passages from the book. According to Taleb, the book's most popular chapter was Chapter 11, the one in which he compressed all the literature on the topic of miscalculating probability. Important point: “it's more random than we think, not it is all random.” Chance favors preparedness, but it is not caused by preparedness (same for hard work, skills, etc.) “This business of journalism is just about entertainment, particularly when it comes to radio and television.” As much as we want to “keep it simple, stupid” … It is precisely the simplification of issues that are actually very complex, which can be dangerous. “Things that happen with little help from luck are more resistant to randomness.” “Mild success can be explainable by skills and labor. Wild success is attributable to variance.” One common theory for why people pursue leadership is because of “social emotions” which cause others to be influenced by a person due to small, almost imperceptible physical signals like charisma, gestures, and gait. This has also been shown via evolutionary psychology: when you perform well in life, you get all “puffed up” in the way you carry yourself, the bounce in your step, etc. From an evolution standpoint this is great because it becomes easier to spot the most successful / desirable mate. The concept of alternative histories is particularly interesting. If you were to relive a set of events 1000 times, what would the range of outcomes be? If there is very little variance in your alternative histories (i.e. You chose to become a dentist and you will probably make more or less the same amount of money and live a similar lifestyle all 1000 times), then you are in a relatively non- random situation. Meanwhile, if there is a very wide range of normal results when considering 1,000 variations (entrepreneurs, traders, etc.), then it is a very random situation. The quality of a choice cannot be judged just by the result. (I first learned this in baseball. Just because a pitch you call or play you call doesn't work out doesn't make it a poor choice. It could have been the right call, but bad luck. Or vice versa.) “Certainty is something that is likely to take place across the highest number of different alternative histories. Uncertainty concerns events that should take place in the lowest number of them.” You should think carefully about getting more insurance / shielding yourself from events that — although unlikely — could be catastrophic. You essentially want to insulate yourself from terrible random accidents. We have a tendency to see risks against specific things as more likely than general risks (dying in a terrorist attack while traveling vs. dying on your next trip, even though the second includes the first). We seem to overvalue the things that trigger an emotional response and undervalue the things that aren't as emotional. We are so mentally wired to overvalue the sensational stories that you can “realize informational gains by dispensing with the news.” Fascinating famous Swiss study of the amnesia patient who couldn't remember doctor's name but did remember him pricking her hand with a pin. “Every man believes that he is quite different.” It's better to value old, distilled thoughts than “new thinking” because for an idea to last so long it must be good. That is, old ideas have had to stand the test of time. New ideas have not. Some new ideas will end up lasting, but most will not. The ratio of undistilled information to distilled is rising. Let's call information that has never had to prove its truth more than once or twice, undistilled. And information that has been filtered through many years, counter arguments, and situations is distilled. You want more distilled information (concepts that stand the test of time and rigorous analysis) and less undistilled information (the news, reactionary opinions, and “cutting edge” research). There is nothing wrong with losing. The problem is losing more than you plan to lose. You need clear rules that limit your downside. (“If any investment loses one million dollars then our firm sells immediately.”) Much of what is randomness is timing. The best strategy for a given time period is often not the best strategy overall. In any given cycle, certain places will be dangerous, certain trading strategies will be fruitful, etc. If you find yourself doing something extraordinarily well in a random situation, then keep doing what's working but limit your downside. There is nothing wrong with benefitting from randomness so long as you protect yourself from negative random events. Randomness means there are some strategies that work well for any given cycle (an extreme fad diet), but these cycles are often short to medium term successes. More importantly, the strategies that work for a given cycle in the short term may not be the best for long run. They are sub optimal strategies winning over a randomly beneficial short term cycle. The same can said for setting huge goals, following a fad diet, chasing an extreme training protocol, and so on. Unsustainable and suboptimal for the long term. In this way, evolutionary traits that are undesirable can survive for a period of time in any given population. That is, suboptimal strategies and traits can seem desirable in the short run even though they will be resoundingly defeated in the long run. Important point: you can never affirm a statement, merely confirm its rejection. There is a big difference between “this has never happened” and “this will ever happen.” You can say the first, but never truly confirm the second. It just takes one counter example to prove all previous observations wrong. We never know things for sure, only with varying degrees of certainty. There are only two types of ideas. Those that have been proven wrong and those which have yet to be proved wrong. (Feynman said something similar.) Strive to become a man of leisure who can afford to sit with ideas, think properly about them, and gradually provide something of value. Science is speculation. This is important to remember. Scientists are simply creating well-formed and well-educated conjectures about the world. But they are still conjectures that can be proved incorrect by one random event. It's a difficult standard to demand that you can actually implement ideas and not merely share them (there have been many brilliant philosophers and scientists who have had great ideas they didn't personally use), but is an idea really that great if you can stick to it? Obviously, everyone has different skills and circumstances, so maybe someone can use your idea even if you can't. But generally speaking, I think you should be able to live out the ideas you share. Pascal: “the optimal strategy for humans is to believe in the existence of God. For, if God exists, then the believer will be rewarded. If God does not exist, the believer will have nothing to lose.” My first thought: “yes, but what if you believe in the ‘wrong' God?” Should you play a numbers game and believe in the God most people believe in? Or, can we safely assume that of the infinite number of possible Gods humans could have designed it is unlikely that any of the ones we worship are actually the God? So, just believe that a higher power exists? Whew. Tough call here. Social treadmill effect: you get rich, move to a better neighborhood, surround yourself with more successful people, and feel poor again. “Remember that nobody accepts randomness in his own success, only his failure.” Skewness and expectations: you can't just look at the odds of something happening, but also the payoff you receive if it works (and the cost of it failing). A bet on something very unlikely can be smart if the payoff is large and you have rules to limit the many small losses that are likely. Minor stalemates in life can often be solved by choosing randomly. In many cases it doesn't really matter so long as you choose something and move forward. We follow rules not because they are the best options, but because they make things fast and easy. Humans are inherently flawed. The cognitive biases that we have are simply a result of how our brains work. Sometimes these biases help us rather than hurt us. But they are always a result of how we are built. That makes them particularly difficult to avoid. We seem to focus too much on “local” changes, not global ones. That is, we care too much about the latest change rather than the overall trend. “Wealth does not make people happy, but positive increases in wealth may.” We do not think, but use heuristics to make decisions. Emotions are “lubricants of reason.” We actually need to feel things to make decisions. Emotions give us energy and they are actually critical to life in the day-to-day world. In other words, the goal here is not to become a robot who can analyze everything with perfect logic. Even if you know about randomness and cognitive biases, you are still just as likely to fall victim to them. How to overcome these biases? We need tricks. We are just animals and we need to re-structure our environment to control our emotions in a smart way. “Most of us know pretty much how we should behave. It is the execution that is the problem, not the absence of knowledge.” “I try to remind my group each week that we are all idiots and know nothing, but we have the good fortune of knowing it.” Do not blame others for your failures. Even if they are at fault. The only aspect of your life that fortune does not have control over is your behavior. Repetitiveness is key for determining if you are seeing skill or randomness at play. Can't repeat it? Not skillful. “We favor the visible, the embedded, the personal, the narrated, and the tangible. We scorn the abstract. Everything good — aesthetics, ethics — and wrong — fooled by randomness — with us seems to flow from it.”
Basic Techniques of Ophthalmic Surgery (3rd Edition) - Original PDF
Basic Techniques of Ophthalmic Surgery (3rd Edition) - Original PDF
نویسندگان: American Academy of Ophthalmology, Jean R. Hausheer خلاصه: This book is a supplement to the required training and experience that is essential for every ophthalmic surgeon to achieve safe and effective outcomes for patients. Correct surgical site marking and “surgical pause,” or “time out,” are not covered in this book, yet must be consistently and accurately implemented by the ophthalmic surgeon. While perioperative ophthalmic medi cations for each procedure are briefly discussed herein, physicians should be mindful to continually explore specific and proper use of medicaments for each procedure, on which there is an exhaustive body of knowledge, since perioperative pharmacology is also evolving alongside surgical procedures themselves.
Medicinal Plants of the Asteraceae Family: Traditional Uses, Phytochemistry and Pharmacological Activities - Original PDF
Medicinal Plants of the Asteraceae Family: Traditional Uses, Phytochemistry and Pharmacological Activities - Original PDF
نویسندگان: Hari Prasad Devkota, Tariq Aftab خلاصه: .1 Introduction Medicinal plants have been an important source of the primary healthcare for prevention and treatment of diseases. Many of these plant species are also used as components of foods, nutraceuticals, functional foods, beverages, cosmetics, dyes, and many other purposes (Khanal et al. 2021). Medicinal plants are one of the important sources of modern drug discovery and development and more than 30% of the drugs currently marketed are derived from natural products (Newman and Cragg 2016; Atanasov et al. 2021).
Rebirth of the Small Family Farm: A Handbook for Starting a Successful Organic Farm Based on the Community Supported Agriculture Concept - Original PDF
Rebirth of the Small Family Farm: A Handbook for Starting a Successful Organic Farm Based on the Community Supported Agriculture Concept - Original PDF
نویسندگان: Bonnie & Bob Gregson خلاصه: Introduction it is, poetically, a dark and stormy October night as this (true) tale begins to be set on paper. We have just shed our raingear and come inside after a session of slaughtering nearly 100 over-the-hill chickens. They are easy to snag from their henhouse perches after dark, and it was slightly comforting to do this periodic unpleasant-but-necessary chore in the rain. How bizarre this thought process — let alone the actual deeds — would have seemed to either of us eight years ago! We were then in our mid-40s, had just remarried and bought a small operating flower and nut farm on an island near Seattle, and were determined to drop out of corporate careers for a better lifestyle. So we did. And life did get better, much better.
Encyclopedia of the History of Psychological Theories - Original PDF
Encyclopedia of the History of Psychological Theories - Original PDF
نویسندگان: Robert W. Rieber خلاصه: Some might argue that in the contemporary clinical practice of psycho- therapy, the focus on evidence-based intervention and effective out- come has overshadowed theory in importance. Maybe. But, at the same time, it is clear that psychotherapists adopt and practice according to one theory or another because their experience (and decades of empirical evidence) suggests that having a sound theory of psychotherapy leads to greater therapeutic success. Theory is fundamental in guiding psycho- therapists in understanding why people behave, think, and feel in certain ways, and it provides the guidance to then contemplate what a client can do to instigate meaningful change. Still, the role of theory in the helping process itself can be hard to explain. This narrative about solving problems may help convey theory’s importance: Aesop tells the fable of the sun and wind having a contest to decide who was the most powerful. From above the earth, they spotted a person walking down the street, and the wind said that he bet he could get the person’s coat off. The sun agreed to the contest. The wind blew, and the person held on tightly to his coat. The more the wind blew, the tighter the person held onto his coat. The sun said it was his turn. She put all of her energy into creating warm sunshine, and soon the person took off his coat
Dark Tourist: Essays - Original PDF
Dark Tourist: Essays - Original PDF
نویسندگان: Hasanthika Sirisena خلاصه: Dark tourism—visiting sites of war, violence, and other traumas experienced by others—takes different forms in Hasanthika Sirisena’s stunning excavation of the unexpected places (and ways) in which personal identity and the riptides of history meet. The 1961 plane crash that left a nuclear warhead buried near her North Carolina hometown, juxtaposed with reflections on her father’s stroke. A visit to Jaffna in Sri Lanka—the country of her birth, yet where she is unmistakably a foreigner—to view sites from the recent civil war, already layered over with the narratives of the victors. A fraught memory of her time as a young art student in Chicago that is uneasily foundational to her bisexual, queer identity today. The ways that life-changing impairments following a severe eye injury have shaped her thinking about disability and self-worth. Deftly blending reportage, cultural criticism, and memoir, Sirisena pieces together facets of her own sometimes-fractured self to find wider resonances with the human universals of love, sex, family, and art—and with language’s ability to both fail and save us. Dark Tourist becomes then about finding a home, if not in the world, at least within the limitless expanse of the page.

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